Effects of Diclofenac, Aceclofenac and meloxicam on the metabolism of proteoglycans and hyaluronan in osteoarthritic human cartilage; Laurent Blot, Annette Marcelis, Jean-Pierre Devogelaer & Daniel-Henri Manicourt; British Journal of Pharmacology, 2000, 131, 1413 -1421 pdf-icon
Hydrolytic Activity Is Essential for Aceclofenac To Inhibit Cyclooxygenase in Rheumatoid Synovial Cells; Ryuta Yamazaki, Shinichi Kawai, Tsuneo Matsumoto, Takeshi Matsuzaki, Shusuke Hashimoto, Teruo Yokokura, Tomihisa Koshino, and Yutaka Mizushima; The Journal of Pharmacology and Experimental Therapeutics, 289:676681, 1999. pdf-icon
P-selectin mediates neutrophil adhesion to endothelial cell borders; Alan R. Burns, Robert A. Bowden, Yasunori Abe, David C. Walker, Scott I. Simon, Mark L. Entman, and C. Wayne Smith; Journal of Leukocyte Biology Volume 65, March 1999; PP. 299-306. pdf-icon
Prevention of post-laminectomy peridural fibrosis with Aceclofenac. An experimental rabbit study; M.A. Sandovala and D. Hernndez-Vaquero; Rev. esp. cir. ortop. Traumatol. 2008;52:99-104. pdf-icon
Benefits and Risks of Ankylosing Spondylitis Treatment With Nonsteroidal Anti-inflammatory Drugs; H. Song, D. A. Poddubnyy, M. Rudwaleit, and J. Sieper; Arthritis & Rheumatism, Vol. 58, No. 4, April 2008, pp 929938. pdf-icon
Recommendations for the use of anti-inflammatory drugs and indications for gastrointestinal protection in emergency departments; Emili Gene, Xavier Calvet, Anisi Moron, Maria Luisa Iglesias; Emergencias 2009; 21: 295-300. pdf-icon
Aceclofenac in The Management of Inflammatory Pain; Erik Legrand; Expert Opin. Pharmacother. (2004), 5(6): 1347-1357 pdf-icon
Interleukin-1, tumor necrosis factor alpha, and interleukin-17 synergistically up-regulate nitric oxide and prostaglandin E2 production in explants of human osteoarthritic knee menisci; LeGrand A, Fermor B, Fink C, Pisetsky DS, Weinberg JB, Vail TP, Guilak F; Arthritis Rheum. 2001 Sep;44(9):2078-83. pdf-icon
In vitro effects of Aceclofenac and its metabolites on the production by chondrocytes of inflammatory mediators; Henrotin Y, de Leval X, Mathy-Hartet M, Mouithys-Mickalad A, Deby-Dupont G, Delarge J, Reginster JY; Inflamm Res. 2001 Aug;50(8):391-9. pdf-icon
Patient and Physician Satisfaction with Aceclofenac: Results of the European Observational Cohort Study (Experience with Aceclofenac for Inflammatory Pain in Daily Practice); Ernst-Martin Lemmel, Burkhard Leeb, Johan De Bast and Spyros Aslanidis; Current Medical Research and Opinion; 2002, Vol. 18, No. 3 , Pages 146-153. pdf-icon
The role of cytokines in osteoarthritis pathophysiology; Fernandes JC, Martel-Pelletier J, Pelletier JP.; Biorheology. 2002;39(1-2):237-46. pdf-icon
Efficacy and safety of Aceclofenac in the treatment of osteoarthritis: a randomized double-blind comparative clinical trial versus Diclofenac an Indian experience; A. Pareek, A. S. Chandanwale, J. Oak, U. K. Jain and S. Kapoor; Current Medical Research and Opinion; 2006, Vol. 22, No. 5 , Pages 977-988. pdf-icon
Non-steroidal anti-inflammatory agents inhibit stimulated neutrophil adhesion to endothelium: adenosine dependent and independent mechanisms; Cronstein BN, Van de Stouwe M, Druska L, Levin RI, Weissmann G.; Inflammation. 1994 Jun;18(3):323-35. pdf-icon
Aceclofenac increases the synthesis of interleukin 1 receptor antagonist and decreases the production of nitric oxide in human articular chondrocytes; E Maneiro, M J Lpez-Armada, J L Fernndez-Sueiro, B Lema, F Galdo, and F J Blanco; The Journal of Rheumatology December 1, 2001 vol. 28 no. 12 2692-2699. pdf-icon
Synthesis and release of human cartilage matrix Proteoglycan are differently regulated by nitric oxide and prostaglandin-E2; S C Mastbergen, J W J Bijlsma, F P J G Lafeber; Ann Rheum Dis 2008;67:52-58. pdf-icon
(A) Aceclofenac in the management of inflammatory pain; Erik Legrand; Current Medical Research and Opinion; June 2004, Vol. 5, No. 6 , Pages 1347-1357.(B) Comparison of Aceclofenac with Diclofenac in the treatment of osteoarthritis; E. Ward, E. M. Veys, J. M. Bowdler and J. Roma; Clinical Rheumatology; Volume 14, Number 6, 656-662, 1995.((C) What is the role of Aceclofenac in the therapeutic arsenal against chronic osteoarthritis pathologies? Reginster JY, Paul I, Henrotin Y.; Rev Med Liege. 2001 Jul;56(7):484-8.(D) Long-term effect of non steroidal anti-inflammatory drugs on the production of cytokines and other inflammatory mediators by blood cells of patients with osteoarthritis; Gonzlez E, de la Cruz C, de Nicols R, Egido J, Herrero-Beaumont G.; Agents Actions. 1994 May;41(3-4):171-8. 

(E) Nitric oxide synthase and cyclooxygenases: distribution, regulation, and intervention in arthritis; Amin AR, Attur M, Abramson SB.; Curr Opin Rheumatol. 1999 May;11(3):202-9.


(F) Patient and physician satisfaction with Aceclofenac: results of the European Observational Cohort Study (experience with Aceclofenac for inflammatory pain in daily practice). Aceclofenac is the treatment of choice for patients and physicians in the management of inflammatory pain; Lemmel EM, Leeb B, De Bast J, Aslanidis S.; Curr Med Res Opin. 2002;18(3):146-53.